- Arsenal are looking to increase pressure on leaders Liverpool
- Newcastle bid to leapfrog Manchester City with Etihad win
- Struggling Spurs and Man Utd clash in London

There are plenty of pressing Premier League issues this weekend at the top and bottom of the table and, at the summit, Arsenal get the chance to pile some pressure on leaders Liverpool.

The Reds succumbed to a late leveller from Everton in the Merseyside derby in midweek and their lead could be cut to four points before they face Wolves on Sunday if the Gunners take care of business at Leicester on Saturday.

Here are our score predictions for all 10 matches being contested in the English top flight on matchday 25.

Brighton vs Chelsea (Friday 8pm)

Chelsea are scrapping to stay in the top four and Enzo Maresca's side are now winless in four on their travels.

Brighton, meanwhile, have not won any of their last five in the league at the Amex, though they did turn over the Blues in the FA Cup here last time out.

Score prediction: Brighton 1-1 Chelsea

Leicester vs Arsenal (Saturday 12.30pm)

Leicester have conceded at least twice in eight of their last nine home games and have lost eight of their last nine Premier League games.

Arsenal have a chance to close the gap on Liverpool and Mikel Arteta knows his side have to take it.

Score prediction: Leicester 0-3 Arsenal

Aston Villa vs Ipswich (Saturday 3.00pm)

Ipswich picked up a point in the reverse game but arrive at Villa Park off the back of four straight league losses which saw them ship 14 goals.

Villa, however, have conceded in their last seven homes games and may be breached on their way to three points.

Score prediction: Aston Villa 3-1 Ipswich

Fulham vs Nottingham Forest (Saturday 3.00pm)

Marco Silva's Fulham are having a fine season despite just four home league wins in 12 attempts.

The Cottagers have not won any of the last five by the River Thames, though, and, in Nottingham Forest, face an opponent flying high in third and seeking an eighth Premier League away win.

Score prediction: Fulham 0-2 Nottingham Forest

Manchester City vs Newcastle (Saturday 3.00pm)

Man City once again showed their defensive frailties in midweek as they snatched defeat from the jaws of victory against Real Madrid.

They are level on points with Newcastle and Eddie Howe's side have won six in a row on the road in all competitions.

Things ended level at St James' Park when they met in September and both managers might just welcome a stalemate again.

Score prediction: Manchester City 2-2 Newcastle

Southampton vs Bournemouth (Saturday 3.00pm)

The Cherries are flying high in seventh place and with aspirations of European football next season as they make the short trip to St Mary's to face a Saints side who have taken just nine of a possible 72 points so far.

Bournemouth have won the last three meetings and can ease to victory.

Score prediction: Southampton 1-3 Bournemouth

West Ham vs Brentford (Saturday 3.00pm)

Both Graham Potter and Thomas Frank have plenty injury worries going into this London derby.

It ended 1-1 when they met at the Gtech Stadium back in September as the Bees failed to capitalise having scored inside a minute, with a repeat scoreline on the cards.

Score prediction: West Ham 1-1 Brentford

Crystal Palace vs Everton (Saturday 5.30pm)

Everton summoned every sinew of their being to grab a point in the final Merseyside derby at Goodison Park on Wednesday, which may take a toll on the Toffees.

Palace have scored only 11 times in 12 home league games, while Everton have netted just seven in 11 on the road.

Score prediction: Crystal Palace 0-0 Everton

Liverpool vs Wolves (Sunday 2.00pm)

Liverpool have endured a rare difficult week with their Merseyside-derby stalemate hot on the heels of an FA Cup exit at Plymouth Argyle.

Only Leicester have conceded more time on the road than Wolves, however, and the Reds have scored at least twice in 16 straight games at Anfield in all competitions.

Score prediction: Liverpool 4-1 Wolves

Tottenham vs Manchester United (Sunday 4.30pm)

Just eight league wins each for these sides in 24 attempts leaves the pair lingering in the bottom half.

For the Red Devils generation that grew up on the mantra of 'It's only Tottenham', five games without a win against Spurs and 13 goals conceded is a reality check.

Ange Postecoglou is unbeaten against United since arriving in north London and has some of his injured stars coming back.

Score prediction: Tottenham 3-1 Manchester United