MLB Wild Card Odds and Preview for Tuesday Night
With the 2025 MLB regular season wrapped up, the Wild Card games have delivered superb entertainment, as well as a plethora of wagering opportunities. In both the American League (AL) and National League (NL), teams are jockeying for positioning, home-field advantages, and favorable matchups. With incredible upcoming matches including tomorrow's game between the Tigers vs Guardians, there is no better time to place your bets on the MLB. Keep reading to learn more.
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MLB Wild Card Round Overview
The MLB Wild Card Series is the first round of the MLB postseason, featuring the six teams from each league that were unsuccessful in their division, but qualified based on their season record. Winners of the Wild Card Round will then advance to the Division Series. This is set to begin on Saturday, October 4. Read below for game overviews for tomorrows schedule.
Preview of Tomorrow’s MLB Games
Please note, that the bet365 Moneyline odds stated below, are accurate from the time of writing on Monday, September 29, and are subject to change.
Tigers vs Guardians @ 1:08 PM ET
DET Tigers -165 Moneyline
CLE Guardians +140 Moneyline
Detroit visits Cleveland to open their Wild Card series in a highly anticipated AL battle. The Tigers, having stumbled late in the season, aim to reset and challenge Cleveland’s momentum. Guardians secured their division after a stunning comeback, sparking confidence among fans and bettors. Pitching and bullpen depth will be key. Detroit’s hitters must crack the Guardians’ pitching staff early. Expect sharp strategic play, with betting interest in Run Line, total runs, and spot starts.
Padres vs Cubs @ 3:08 PM ET
CHI Cubs -115 Moneyline
In the NL Wild Card opener, the San Diego Padres face the Chicago Cubs at Wrigley Field. Both clubs enter with postseason hunger, the Padres with firepower and the Cubs riding home support. San Diego’s rotation and bullpen arms will be under scrutiny, while Chicago will lean on clutch hitting and home advantage. Watch for prop bets like extra innings, player RBI totals, and bullpen matchups in late innings.
Red Sox vs Yankees @ 6:08 PM ET
BOS Red Sox +110 Moneyline
NY Yankees -130 Moneyline
A classic rivalry fuels this AL Wild Card game. Boston’s offense, led by Masataka Yoshida and David Hamilton, enters red-hot. New York counters with deep pitching and postseason experience. The Red Sox dominated the season series, but Yankee Stadium is a different stage. Expect tension, pitching duels, and high leverage moments. Total runs and pitcher strikeout props will draw strong wagering interest.
Reds vs Dodgers @ 9:08 PM ET
CIN Reds +150 Moneyline
LA Dodgers -180 Moneyline
Cincinnati opens its postseason journey at Los Angeles. The Reds clinched a Wild Card spot despite a late slump, while the Dodgers bring veteran poise and home-field advantage. LA’s rotation is loaded, and their bullpen is battle-tested. Can the Reds find offense early and force the Dodgers into extended use of relievers? The matchup is primed for sharp betting angles on innings prop, bullpen failures, and run totals.
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