• Tottenham won the Europa League but lost on penalties to PSG in the UEFA Super Cup

• Villarreal's former Arsenal winger Nicolas Pepe was LaLiga's August Player of the Month

• Recommended bet: Tie/Tottenham Half Time/Full Time

The first week of Champions League fixtures features four England-Spain clashes including Tottenham's home game against Villarreal on Tuesday.

Spurs finished 17th in the Premier League last season but earned their place in the Champions League thanks to a 1-0 win over Manchester United in the Europa League final.

They have made a solid start under new manager Thomas Frank but face a competitive Villarreal side who won their final six matches of 2024-25 to seal a top-five finish in LaLiga.

The latest Tottenham vs Villarreal odds are available on LiveScore Bet.

Team news

Tottenham will assess the fitness of striker Dominic Solanke, who has missed their last two matches with an ankle injury.

Mathys Tel is not in the Champions League squad so Richarlison should start up front and Dejan Kulusevski, Yves Bissouma, James Maddison, Radu Dragusin and Kota Takai are injured.

Villarreal will be without the injured Logan Costa, Pau Cabanes, Gerard Moreno and Willy Kambwala but Tottenham loanee Manor Solomon is eligible to play.

The latest Tottenham vs Villarreal odds are available on LiveScore Bet.

The stats

Tottenham have won three of their first four Premier League matches to nil.

Both teams have scored in only two of Tottenham's last 10 games in all competitions.

Spurs have opened the scoring in six of their last seven matches.

Villarreal have conceded only one first-half goal in four games this season.

The Yellow Submarine have won eight of their last 10 matches in LaLiga.

Villarreal have lost only two of their last 15 games.

The latest Tottenham vs Villarreal odds are available on LiveScore Bet.

Prediction

Ange Postecoglou led Tottenham to Europa League glory last season and his successor Thomas Frank is targeting a memorable Champions League campaign in 2025-26.

Spurs are clear favourites for their Matchday 1 home game against Villarreal although they may have to wait until the second half to take charge.

Former Brentford boss Frank has made a promising start in north London, masterminding Premier League victories to nil against Burnley, Manchester City and West Ham.

He has benefited from the availability of first-choice centre-backs Cristian Romero and Micky van de Ven and the improved form of full-back Djed Spence.

Spurs were seconds away from beating European champions Paris Saint-Germain in last month's UEFA Super Cup before conceding a late equaliser and losing on penalties.

They were outplayed by Bournemouth in a 1-0 home defeat just before the international break but roared back with a 3-0 win at 10-man West Ham on Saturday.

All three goals at the London Stadium came after half-time and Tottenham may need to be patient to break down Villarreal.

Marcelino's men won their last six games in LaLiga last term to seal Champions League qualification and they kicked off the new campaign by beating Real Oviedo 2-0 and Girona 5-0 at home.

They have been less convincing on the road, drawing 1-1 at Celta Vigo before Saturday's 2-0 loss at Atletico Madrid, where they managed only one shot on target.

Defensive injuries may hamper Villarreal against Tottenham, who could line up with an exciting front four of Mohammed Kudus, Xavi Simons, Brennan Johnson and Richarlison.

France striker Randal Kolo Muani, signed on deadline day, is a potential game-changer off the bench for Spurs and they can grind out a victory over a solid but unspectacular Villarreal side.   

Back Tie/Tottenham Half Time/Full Time, available at 19/5 with LiveScore Bet.

The latest Tottenham vs Villarreal odds are available on LiveScore Bet.